UniprotKB/SwissProt ID: P04275 (P04275)
Gene Name:
VWF
Organism: Homo sapiens (Human)
Function: Important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet-surface receptor complex GPIb-IX-V. Also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Secreted. Secreted, extracellular space, extracellular matrix
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