Protein Name:
Myoglobin
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UniprotKB/SwissProt ID: P04247 (P04247)
Gene Name:
Mb
Organism: Mus musculus (Mouse)
Function: Monomeric heme protein which primary function is to store oxygen and facilitate its diffusion within muscle tissues. Reversibly binds oxygen through a pentacoordinated heme iron and enables its timely and efficient release as needed during periods of heightened demand (PubMed:10468637, PubMed:11304494). Depending on the oxidative conditions of tissues and cells, and in addition to its ability to bind oxygen, it also has a nitrite reductase activity whereby it regulates the production of bioactive nitric oxide (By similarity). Under stress conditions, like hypoxia and anoxia, it also protects cells against reactive oxygen species thanks to its pseudoperoxidase activity (PubMed:15132981)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm, sarcoplasm
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of P04247
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
67 |
KGSEDLKKHG C TVLTALGTIL |
CCCCCCCEEE E EEEEEEHHHH |
2.08% |
21278135
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