UniprotKB/SwissProt ID: P04191 (P04191)
Gene Name:
ATP2A1
Organism: Oryctolagus cuniculus (Rabbit)
Function: Key regulator of striated muscle performance by acting as the major Ca(2+) ATPase responsible for the reuptake of cytosolic Ca(2+) into the sarcoplasmic reticulum. Catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen (PubMed:10914677, PubMed:11438520, PubMed:15189864, PubMed:18075584, PubMed:23996003, PubMed:24270570, PubMed:29081402). Contributes to calcium sequestration involved in muscular excitation/contraction
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Endoplasmic reticulum membrane. Sarcoplasmic reticulum membrane
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