UniprotKB/SwissProt ID: P04021 (P04021)
Gene Name:
OPG057
Organism: Vaccinia virus (strain Western Reserve) (VACV)
Function: Major envelope protein that plays a role in the biogenesis of the viral double membrane and in egress of virus from the host cell (PubMed:17475658, PubMed:27466413, PubMed:8999886). Produces the wrapped form of virus that is required for cell-to-cell spread (PubMed:27466413, PubMed:29540596). Acts as a lipase with broad specificity including phospholipase C, phospholipase A, and triacylglycerol lipase activities (PubMed:9405398)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Virion membrane. Host Golgi apparatus, host trans-Golgi network. Host endoplasmic reticulum membrane
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