Protein Name:
C4b-binding protein alpha chain
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UniprotKB/SwissProt ID: P04003 (P04003)
Gene Name:
C4BPA
Organism: Homo sapiens (Human)
Function: Controls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b. It also accelerates the degradation of the C4bC2a complex (C3 convertase) by dissociating the complement fragment C2a. Alpha chain binds C4b. It also interacts with anticoagulant protein S and with serum amyloid P component
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Secreted
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Graphical Visualization of S-nitrosylation Sites:
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