\
logo
  Home | Contact us | Browse | Quick Search by UniProtKB ID, Keyword, PDBID

Menu:

Latest news:

Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

Read more...


Protein Name: Serotransferrin
UniprotKB/SwissProt ID: P02787 (P02787)

Gene Name: TF

Organism: Homo sapiens (Human)

Function: Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation (Microbial infection) Serves as an iron source for Neisseria species, which capture the protein and extract its iron for their own use (Microbial infection) Serves as an iron source for parasite T.brucei (strain 427), which capture TF via its own transferrin receptor ESAG6:ESAG7 and extract its iron for its own use

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Secreted

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR030685 Serotransferrin_mammal
IPR016357 Transferrin
IPR001156 Transferrin-like_dom
IPR018195 Transferrin_Fe_BS
The S-nitrosylation sites of P02787
No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 137 QMNQLRGKKS C HTGLGRSAGW  CHHHHHHHHH H HHHHHHHHCC  4.59% 25040305
2 213 QYFGYSGAFK C LKDGAGDVAF  CHHHHHHHHH H HHHHHHHHCC  4.63% 25040305
3 246 KADRDQYELL C LDNTRKPVDE  CHHHHHHHHH H HHHHHHHHCC  7.58% 25040305
4 260 TRKPVDEYKD C HLAQVPSHTV  CHHHHHHHHH H HHHHHHHHCC  2.18% 25040305
5 364 PTDECKPVKW C ALSHHERLKC  CHHHHHHHHH H HHHHHHHHCC  1.95% 25040305
6 374 CALSHHERLK C DEWSVNSVGK  CHHHHHHHHH H HHHHHHHHCC  7.3% 25040305
7 396 ECVSAETTED C IAKIMNGEAD  CHHHHHHHHH H HHHHHHHHCC  2.37% 25040305
8 503 CRFDEFFSEG C APGSKKDSSL  CHHHHHHHHH H HHHHHHHHCC  3.47% 25040305
9 525 KLCMGSGLNL C EPNNKEGYYG  CHHHHHHHHH H HHHHHHHHCC  8.76% 25040305
10 58 VIPSDGPSVA C VKKASYLDCI  CHHHHHHHHH H HHHHHHHHCC  4.29% 25040305
11 582 NLNEKDYELL C LDGTRKPVEE  CHHHHHHHHH H HHHHHHHHCC  5.21% 25040305
12 596 TRKPVEEYAN C HLARAPNHAV  CHHHHHHHHH H HHHHHHHHCC  1.8% 25040305
13 684 YVKAVGNLRK C STSSLLEACT  CHHHHHHHHH H HHHHHHHHCC  4.3% 25040305