Protein Name:
Collagen alpha-1(IV) chain
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UniprotKB/SwissProt ID: P02463 (P02463)
Gene Name:
Col4a1
Organism: Mus musculus (Mouse)
Function: Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen Arresten, comprising the C-terminal NC1 domain, inhibits angiogenesis and tumor formation. The C-terminal half is found to possess the anti-angiogenic activity. Specifically inhibits endothelial cell proliferation, migration and tube formation
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Secreted, extracellular space, extracellular matrix, basement membrane
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of P02463
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
1460 |
RHSQTTDDPL C PPGTKILYHG |
CCHHHHHHHH H HHHHHHHHHH |
4.68% |
21278135
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| 2 |
1493 |
HGQDLGTAGS C LRKFSTMPFL |
CCHHHHHHHH H HHHHHHHHHH |
4.1% |
21278135
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