Protein Name:
GTPase KRas
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UniprotKB/SwissProt ID: P01116 (P01116)
Gene Name:
KRAS
Organism: Homo sapiens (Human)
Function: Ras proteins bind GDP/GTP and possess intrinsic GTPase activity (PubMed:20949621, PubMed:39809765). Plays an important role in the regulation of cell proliferation (PubMed:22711838, PubMed:23698361). Plays a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs) in colorectal cancer (CRC) cells in a ZNF304-dependent manner (PubMed:24623306)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cell membrane. Endomembrane system. Cytoplasm, cytosol. Cell membrane
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of P01116
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
80 |
QYMRTGEGFL C VFAINNTKSF |
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