Protein Name:
Argininosuccinate synthase
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UniprotKB/SwissProt ID: P00966 (P00966)
Gene Name:
ASS1
Organism: Homo sapiens (Human)
Function: One of the enzymes of the urea cycle, the metabolic pathway transforming neurotoxic amonia produced by protein catabolism into inocuous urea in the liver of ureotelic animals. Catalyzes the formation of arginosuccinate from aspartate, citrulline and ATP and together with ASL it is responsible for the biosynthesis of arginine in most body tissues
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm, cytosol
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of P00966
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
132 |
GNDQVRFELS C YSLAPQIKVI |
CCCCCEEEEE E CCCCCCEEEE |
4.12% |
22178444
15192091
15688001
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| 2 |
331 |
VYTGFWHSPE C EFVRHCIAKS |
CCCCCEEEEE E CCCCCCEEEE |
5.81% |
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| 3 |
97 |
YLLGTSLARP C IARKQVEIAQ |
CCCCCEEEEE E CCCCCCEEEE |
2.94% |
24105792
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