Protein Name:
Cathepsin B
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UniprotKB/SwissProt ID: P00787 (P00787)
Gene Name:
Ctsb
Organism: Rattus norvegicus (Rat)
Function: Thiol protease which is believed to participate in intracellular degradation and turnover of proteins (PubMed:1639824). Cleaves matrix extracellular phosphoglycoprotein MEPE (By similarity). Involved in the solubilization of cross-linked TG/thyroglobulin in the thyroid follicle lumen (By similarity). Has also been implicated in tumor invasion and metastasis (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Lysosome. Melanosome. Secreted, extracellular space. Apical cell membrane
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of P00787
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
105 |
TIAQIRDQGS C GSCWAFGAVE |
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| 2 |
211 |
EGDTPKCNKM C EAGYSTSYKE |
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| 3 |
93 |
SFDAREQWSN C PTIAQIRDQG |
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