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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Haptoglobin-related protein

UniprotKB/SwissProt ID: P00739 (P00739)

Gene Name: HPR

Organism: Homo sapiens (Human)

Function: Primate-specific plasma protein associated with apolipoprotein L-I (apoL-I)-containing high-density lipoprotein (HDL). This HDL particle, termed trypanosome lytic factor-1 (TLF-1), mediates human innate immune protection against many species of African trypanosomes. Binds hemoglobin with high affinity and may contribute to the clearance of cell-free hemoglobin to allow hepatic recycling of heme iron

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Secreted

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR008292 Haptoglobin
IPR009003 Peptidase_S1_PA
IPR043504 Peptidase_S1_PA_chymotrypsin
IPR001314 Peptidase_S1A
IPR035976 Sushi/SCR/CCP_sf
IPR001254 Trypsin_dom

The S-nitrosylation sites of P00739

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 91 GDKLPECEAV C GKPKNPANPV