Protein Name:
Adenylate kinase isoenzyme 1
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UniprotKB/SwissProt ID: P00568 (P00568)
Gene Name:
AK1
Organism: Homo sapiens (Human)
Function: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity) (PubMed:21080915, PubMed:23416111, PubMed:2542324). Also catalyzes at a very low rate the synthesis of thiamine triphosphate (ThTP) from thiamine diphosphate (ThDP) and ADP (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of P00568
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
187 |
GSVDSVFSQV C THLDALK--- |
CHHHHCCCEE E EEECCCCCCC |
1.21% |
24105792
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| 2 |
25 |
GGPGSGKGTQ C EKIVQKYGYT |
CHHHHCCCEE E EEECCCCCCC |
6.05% |
24105792
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