Protein Name:
Aspartate aminotransferase, mitochondrial
|
UniprotKB/SwissProt ID: P00505 (P00505)
Gene Name:
GOT2
Organism: Homo sapiens (Human)
Function: Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA). As a member of the malate-aspartate shuttle, it has a key role in the intracellular NAD(H) redox balance. Is important for metabolite exchange between mitochondria and cytosol, and for amino acid metabolism. Facilitates cellular uptake of long-chain free fatty acids
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Mitochondrion matrix. Cell membrane
|
|
|
Graphical Visualization of S-nitrosylation Sites:
|
|
The S-nitrosylation sites of P00505
|
| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
106 |
YLPIGGLAEF C KASAELALGE |
CCCCCCCCCC C CHHHHHCHHH |
2.44% |
37478858
|
| 2 |
187 |
QGYRYYDPKT C GFDFTGAVED |
CCCCCCCCCC C CHHHHHCHHH |
6.8% |
19483679
|
| 3 |
272 |
RHFIEQGINV C LCQSYAKNMG |
CCCCCCCCCC C CHHHHHCHHH |
2.45% |
|
| 4 |
295 |
GERVGAFTMV C KDADEAKRVE |
CCCCCCCCCC C CHHHHHCHHH |
1.99% |
|
|
