\
logo
  Home | Contact us | Browse | Quick Search by UniProtKB ID, Keyword, PDBID

Menu:

Latest news:

Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

Read more...


Protein Name: Hypoxanthine-guanine phosphoribosyltransferase

UniprotKB/SwissProt ID: P00493 (P00493)

Gene Name: Hprt1

Organism: Mus musculus (Mouse)

Function: Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate. Transfers the 5-phosphoribosyl group from 5-phosphoribosylpyrophosphate onto the purine. Plays a central role in the generation of purine nucleotides through the purine salvage pathway (By similarity)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR050408 HGPRT
IPR005904 Hxn_phspho_trans
IPR000836 PRibTrfase_dom
IPR029057 PRTase-like

The S-nitrosylation sites of P00493

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 106 TVDFIRLKSY C NDQSTGDIKV  CCCCCCCEEE C CCCCCCCCEE  6.13% 22178444
19101475
2 206 NEYFRDLNHV C VISETGKAKY  CCCCCCCEEE C CCCCCCCCEE  1.42%