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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Phosphatidylserine lipase ABHD16A

UniprotKB/SwissProt ID: O95870 (O95870)

Gene Name: ABHD16A

Organism: Homo sapiens (Human)

Function: Phosphatidylserine (PS) lipase that mediates the hydrolysis of phosphatidylserine to generate lysophosphatidylserine (LPS) (By similarity). LPS constitutes a class of signaling lipids that regulates immunological and neurological processes (By similarity). Has no activity towards diacylglycerol, triacylglycerol or lysophosphatidylserine lipase (PubMed:25290914). Also has monoacylglycerol lipase activity, with preference for 1-(9Z,12Z-octadecadienoyl)-glycerol (1-LG) and 2-glyceryl-15-deoxy-Delta(12,14)-prostaglandin J2 (15d-PGJ(2)-G) (PubMed:25290914)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Membrane

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR000073 AB_hydrolase_1
IPR029058 AB_hydrolase_fold
IPR054518 ABHD16_N

The S-nitrosylation sites of O95870

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 258 CNGRRAKLLA C DGNEIDTMFV   
2 416 HLNLNNAEQL C RYQGPVLLIR