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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Polypyrimidine tract-binding protein 3

UniprotKB/SwissProt ID: O95758 (O95758)

Gene Name: PTBP3

Organism: Homo sapiens (Human)

Function: RNA-binding protein that mediates pre-mRNA alternative splicing regulation. Plays a role in the regulation of cell proliferation, differentiation and migration. Positive regulator of EPO-dependent erythropoiesis. Participates in cell differentiation regulation by repressing tissue-specific exons. Promotes FAS exon 6 skipping. Binds RNA, preferentially to both poly(G) and poly(U)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization:

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR006536 HnRNP-L/PTB
IPR012677 Nucleotide-bd_a/b_plait_sf
IPR021790 PTBP1-like_RRM2
IPR033110 PTBP3_RRM4
IPR035979 RBD_domain_sf
IPR034326 ROD1_RRM1
IPR000504 RRM_dom

The S-nitrosylation sites of O95758

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 249 LDGQNIYNAC C TLRIDFSKLT   
2 68 SRVLHLRKIP C DVTEAEIISL