Protein Name:
Pre-mRNA-splicing factor SLU7
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UniprotKB/SwissProt ID: O95391 (O95391)
Gene Name:
SLU7
Organism: Homo sapiens (Human)
Function: Required for pre-mRNA splicing as component of the spliceosome (PubMed:10197984, PubMed:28502770, PubMed:30705154). Participates in the second catalytic step of pre-mRNA splicing, when the free hydroxyl group of exon I attacks the 3'-splice site to generate spliced mRNA and the excised lariat intron. Required for holding exon 1 properly in the spliceosome and for correct AG identification when more than one possible AG exists in 3'-splicing site region. May be involved in the activation of proximal AG. Probably also involved in alternative splicing regulation
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus. Nucleus speckle. Cytoplasm
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of O95391
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
469 |
AGKEIVNSEE C IINEITGEES |
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