Protein Name:
Transforming acidic coiled-coil-containing protein 2
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UniprotKB/SwissProt ID: O95359 (O95359)
Gene Name:
TACC2
Organism: Homo sapiens (Human)
Function: Plays a role in the microtubule-dependent coupling of the nucleus and the centrosome. Involved in the processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors (By similarity). May play a role in organizing centrosomal microtubules. May act as a tumor suppressor protein. May represent a tumor progression marker
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of O95359
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
1011 |
LEEGSQHEEA C QRHPGASEAA |
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| 2 |
1269 |
ADPRAPGESP C PVGEPPLALE |
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| 3 |
1632 |
GVPGHVPRST C APSPQREVLT |
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| 4 |
1719 |
ITLSTAETQA C ASGDLPEAGT |
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| 5 |
1751 |
VLPGSCQDPA C SDKAPGMEGT |
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| 6 |
1936 |
GDRVEASTPS C PDPAKDLSRS |
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| 7 |
214 |
PLREPMKAPL C GEGDQPGGFE |
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| 8 |
2203 |
LEPAVGPKAA C PLDSESAEGV |
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| 9 |
2573 |
PVRMSESPTP C SGSSFEETEA |
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| 10 |
2859 |
FRKNEEVLKR C AQEYLSRVKK |
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| 11 |
59 |
SIGSVGLGGF C TASESSASLD |
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| 12 |
750 |
STLEIRKMGS C DGEGLLTSPD |
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