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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Structural maintenance of chromosomes protein 2

UniprotKB/SwissProt ID: O95347 (O95347)

Gene Name: SMC2

Organism: Homo sapiens (Human)

Function: Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus. Cytoplasm. Chromosome

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR027417 P-loop_NTPase
IPR003395 RecF/RecN/SMC_N
IPR024704 SMC
IPR027120 Smc2_ABC
IPR010935 SMC_hinge
IPR036277 SMC_hinge_sf

The S-nitrosylation sites of O95347

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 1174 GVSTVARFTQ C QNGKISKEAK   
2 132 ANNTRVQDLF C SVGLNVNNPH   
3 326 AFDLKKKNLA C EESKRKELEK   
4 585 IIPLNKISAR C IAPETLRVAQ   
5 630 MEFVFGTTFV C DNMDNAKKVA