Protein Name:
Golgi SNAP receptor complex member 1
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UniprotKB/SwissProt ID: O95249 (O95249)
Gene Name:
GOSR1
Organism: Homo sapiens (Human)
Function: Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor. May play a protective role against hydrogen peroxide induced cytotoxicity under glutathione depleted conditions in neuronal cells by regulating the intracellular ROS levels via inhibition of p38 MAPK (MAPK11, MAPK12, MAPK13 and MAPK14). Participates in docking and fusion stage of ER to cis-Golgi transport. Plays an important physiological role in VLDL-transport vesicle-Golgi fusion and thus in VLDL delivery to the hepatic cis-Golgi
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Golgi apparatus membrane
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Graphical Visualization of S-nitrosylation Sites:
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| InterPro ID |
Domain Name |
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IPR023601
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Golgi_SNAP_su1 |
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