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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Ubiquitin conjugation factor E4 B

UniprotKB/SwissProt ID: O95155 (O95155)

Gene Name: UBE4B

Organism: Homo sapiens (Human)

Function: Ubiquitin-protein ligase that probably functions as an E3 ligase in conjunction with specific E1 and E2 ligases (By similarity). May also function as an E4 ligase mediating the assembly of polyubiquitin chains on substrates ubiquitinated by another E3 ubiquitin ligase (By similarity). May regulate myosin assembly in striated muscles together with STUB1 and VCP/p97 by targeting myosin chaperone UNC45B for proteasomal degradation (PubMed:17369820)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm. Nucleus

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR019474 Ub_conjug_fac_E4_core
IPR045132 UBE4
IPR003613 Ubox_domain
IPR013083 Znf_RING/FYVE/PHD

The S-nitrosylation sites of O95155

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 113 SQSMDIDGVS C EKSMSQVDVD   
2 581 LWLPKSLSPG C GRELQRLSYL