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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Protein transport protein Sec31A

UniprotKB/SwissProt ID: O94979 (O94979)

Gene Name: SEC31A

Organism: Homo sapiens (Human)

Function: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER) (PubMed:10788476). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm. Cytoplasmic vesicle, COPII-coated vesicle membrane. Endoplasmic reticulum membrane. Cytoplasm, cytosol

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR024298 Sec16_Sec23-bd
IPR040251 SEC31-like
IPR015943 WD40/YVTN_repeat-like_dom_sf
IPR036322 WD40_repeat_dom_sf
IPR001680 WD40_rpt

The S-nitrosylation sites of O94979

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 1130 KTTFEDLIQR C LSSATDPQTK  CCHHHCCHHH H HHCCHHHCCC  2.18% 24105792
2 173 AKTQPPEDIS C IAWNRQVQHI  CCHHHCCHHH H HHCCHHHCCC  2.22%
3 458 AVQSQGFINY C QKKIDASQTE  CCHHHCCHHH H HHCCHHHCCC  4.06%
4 60 LSDPSLDMKS C ATFSSSHRYH  CCHHHCCHHH H HHCCHHHCCC  3.27% 19483679
5 644 MKNWKEIVES C DLKNWREALA  CCHHHCCHHH H HHCCHHHCCC  4.49%
6 704 CAGNVEKLVA C WTKAQDGSHP  CCHHHCCHHH H HHCCHHHCCC  3.55%