Protein Name:
Microtubule cross-linking factor 2
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UniprotKB/SwissProt ID: O94964 (O94964)
Gene Name:
MTCL2
Organism: Homo sapiens (Human)
Function: Microtubule-associated factor that enables integration of the centrosomal and Golgi-associated microtubules on the Golgi membrane, supporting directional migration. Preferentially acts on the perinuclear microtubules accumulated around the Golgi. Associates with the Golgi membrane through the N-terminal coiled-coil region and directly binds microtubules through the C-terminal domain (By similarity). Required for faithful chromosome segregation during mitosis (PubMed:33587225). Regulates autophagy by playing a role in the reduction of glucose production in an adiponectin- and insulin-dependent manner (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm, cytoskeleton. Golgi apparatus membrane. Midbody. Secreted
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of O94964
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
964 |
INAQHSDNKA C TGDSWTQNTP |
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