Protein Name:
Pre-mRNA-processing factor 6
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UniprotKB/SwissProt ID: O94906 (O94906)
Gene Name:
PRPF6
Organism: Homo sapiens (Human)
Function: Involved in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex, one of the building blocks of the spliceosome (PubMed:20118938, PubMed:21549338, PubMed:28781166). Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but does not affect estrogen-induced transactivation
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus, nucleoplasm. Nucleus speckle
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of O94906
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
513 |
REQWIQDAEE C DRAGSVATCQ |
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| 2 |
522 |
ECDRAGSVAT C QAVMRAVIGI |
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