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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: N(G),N(G)-dimethylarginine dimethylaminohydrolase 1

UniprotKB/SwissProt ID: O94760 (O94760)

Gene Name: DDAH1

Organism: Homo sapiens (Human)

Function: Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization:

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR033199 DDAH-like

The S-nitrosylation sites of O94760

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 178 VADGLHLKSF C SMAGPNLIAI  CCCCCCCCHH H HHHHHHHHHC  3.34%
2 222 LTVPDDIAAN C IYLNIPNKGH  CCCCCCCCHH H HHHHHHHHHC  1.53% 22178444
12441345
3 274 ELEKVDGLLT C CSVLINKKVD  CCCCCCCCHH H HHHHHHHHHC  1.32% 22178444
12441345
4 275 LEKVDGLLTC C SVLINKKVDS  CCCCCCCCHH H HHHHHHHHHC  2.38%