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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial

UniprotKB/SwissProt ID: O88986 (O88986)

Gene Name: Gcat

Organism: Mus musculus (Mouse)

Function: Pyridoxal phosphate (PLP) dependent enzyme, which catalyzes the cleavage of 2-amino-3-oxobutanoate to glycine and acetyl-CoA. Catalyzes the second reaction step on the main metabolic degradation pathway for L-threonine

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Mitochondrion. Nucleus

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR011282 2am3keto_CoA_ligase
IPR001917 Aminotrans_II_pyridoxalP_BS
IPR004839 Aminotransferase_I/II_large
IPR050087 AON_synthase_class-II
IPR015424 PyrdxlP-dep_Trfase
IPR015421 PyrdxlP-dep_Trfase_major
IPR015422 PyrdxlP-dep_Trfase_small

The S-nitrosylation sites of O88986

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 103 GAGLSSTRFI C GTQSIHKNLE   
2 26 RAHSALAQLR C ILDSELEGIR