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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Neuronal migration protein doublecortin

UniprotKB/SwissProt ID: O88809 (O88809)

Gene Name: Dcx

Organism: Mus musculus (Mouse)

Function: Microtubule-associated protein required for initial steps of neuronal dispersion and cortex lamination during cerebral cortex development. May act by competing with the putative neuronal protein kinase DCLK1 in binding to a target protein. May in that way participate in a signaling pathway that is crucial for neuronal interaction before and during migration, possibly as part of a calcium ion-dependent signal transduction pathway. May participate along with PAFAH1B1/LIS-1 in a distinct overlapping signaling pathway that promotes neuronal migration

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm. Cell projection, neuron projection

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR017302 DCX_chordates
IPR003533 Doublecortin_dom
IPR036572 Doublecortin_dom_sf