\
logo
  Home | Contact us | Browse | Quick Search by UniProtKB ID, Keyword, PDBID

Menu:

Latest news:

Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

Read more...


Protein Name: Serine/threonine-protein kinase 16

UniprotKB/SwissProt ID: O88697 (O88697)

Gene Name: Stk16

Organism: Mus musculus (Mouse)

Function: Membrane-associated protein kinase that phosphorylates on serine and threonine residues. In vitro substrates include DRG1, ENO1 and EIF4EBP1. Also autophosphorylates (By similarity). May be involved in secretory vesicle trafficking or intracellular signaling. May have a role in regulating stromal-epithelial interactions that occur during ductal morphogenesis in the mammary gland. May be involved in TGF-beta signaling. Able to autophosphorylate on Tyr residue; it is however unclear whether it has tyrosine-protein kinase toward other proteins

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm, perinuclear region. Membrane

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR011009 Kinase-like_dom_sf
IPR000719 Prot_kinase_dom
IPR052239 Ser/Thr-specific_kinases
IPR008271 Ser/Thr_kinase_AS