Protein Name:
Catechol O-methyltransferase
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UniprotKB/SwissProt ID: O88587 (O88587)
Gene Name:
Comt
Organism: Mus musculus (Mouse)
Function: Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm. Cell membrane
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of O88587
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
200 |
YLPDTLLLEE C GLLRKGTVLL |
CHHHHHHHHH H HHHHHHHHHH |
3.21% |
21278135
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| 2 |
234 |
AYVRGSSSFE C THYSSYLEYM |
CHHHHHHHHH H HHHHHHHHHH |
2.4% |
22178444
21278135
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