Protein Name:
Scaffold attachment factor B1
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UniprotKB/SwissProt ID: O88453 (O88453)
Gene Name:
Safb
Organism: Rattus norvegicus (Rat)
Function: Binds to scaffold/matrix attachment region (S/MAR) DNA and forms a molecular assembly point to allow the formation of a 'transcriptosomal' complex (consisting of SR proteins and RNA polymerase II) coupling transcription and RNA processing (By similarity). Functions as an estrogen receptor corepressor and can also bind to the HSP27 promoter and decrease its transcription (By similarity). Thereby acts as a negative regulator of cell proliferation (By similarity). When associated with RBMX, binds to and stimulates transcription from the SREBF1 promoter (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of O88453
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
224 |
EKILDILGET C KSEPVKEEGS |
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| 2 |
384 |
DDVKKFAFDA C NDVPAAPKES |
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| 3 |
470 |
VTNARSPGAR C YGFVTMSTAE |
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