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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Adenylate cyclase type 1

UniprotKB/SwissProt ID: O88444 (O88444)

Gene Name: Adcy1

Organism: Mus musculus (Mouse)

Function: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. Mediates responses to increased cellular Ca(2+)/calmodulin levels (PubMed:7816821, PubMed:9662407). May be involved in regulatory processes in the central nervous system (PubMed:9662407). May play a role in memory and learning (PubMed:7816821). Plays a role in the regulation of the circadian rhythm of daytime contrast sensitivity probably by modulating the rhythmic synthesis of cyclic AMP in the retina (PubMed:24048828)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Membrane. Cell membrane. Cytoplasm. Membrane raft

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR001054 A/G_cyclase
IPR018297 A/G_cyclase_CS
IPR032628 AC_N
IPR030672 Adcy
IPR029787 Nucleotide_cyclase