Protein Name:
Tumor necrosis factor receptor superfamily member 6
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UniprotKB/SwissProt ID: O77736 (O77736)
Gene Name:
FAS
Organism: Sus scrofa (Pig)
Function: Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase CASP8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs CASP8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cell membrane. Membrane raft
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Graphical Visualization of S-nitrosylation Sites:
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