UniprotKB/SwissProt ID: O77590 (O77590)
Gene Name:
AGTR1
Organism: Ovis aries (Sheep)
Function: Receptor for angiotensin II, a vasoconstricting peptide, which acts as a key regulator of blood pressure and sodium retention by the kidney. The activated receptor in turn couples to G-alpha proteins G(q) (GNAQ, GNA11, GNA14 or GNA15) and thus activates phospholipase C and increases the cytosolic Ca(2+) concentrations, which in turn triggers cellular responses such as stimulation of protein kinase C
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cell membrane
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