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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Pleckstrin homology domain-containing family F member 1 homolog

UniprotKB/SwissProt ID: O76902 (O76902)

Gene Name: rush

Organism: Drosophila melanogaster (Fruit fly)

Function: Functions in the regulation of endosome morphology and late endosome formation. Has a role in controlling trafficking from early to late endosomes and from late endosomes to lysosomes. Important for localization of Gdi to the endosomal membranes. May function in controlling the activity of multiple regulators in the endocytic pathway, perhaps by positively controlling those involved in the early steps of endocytosis such as Rab5 and hrs, and negative regulating those involved in the late stages of endocytosis like car and VhaSFD

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Apical cell membrane. Endosome membrane. Cytoplasm, cell cortex

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR011993 PH-like_dom_sf
IPR001849 PH_domain
IPR051765 PH_domain-containing_F
IPR037871 PH_Phafin
IPR055251 SOS1_NGEF_PH
IPR000306 Znf_FYVE
IPR017455 Znf_FYVE-rel
IPR011011 Znf_FYVE_PHD
IPR013083 Znf_RING/FYVE/PHD