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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: WD repeat and HMG-box DNA-binding protein 1

UniprotKB/SwissProt ID: O75717 (O75717)

Gene Name: WDHD1

Organism: Homo sapiens (Human)

Function: Core replisome component that acts as a replication initiation factor. Binds directly to the CMG complex and functions as a hub to recruit additional proteins to the replication fork

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus, nucleoplasm

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR055339 HMG-box_WDHD1
IPR009071 HMG_box_dom
IPR036910 HMG_box_dom_sf
IPR015943 WD40/YVTN_repeat-like_dom_sf
IPR019775 WD40_repeat_CS
IPR036322 WD40_repeat_dom_sf
IPR001680 WD40_rpt
IPR022100 WDHD1/CFT4_beta-prop_2nd
IPR048591 WDHD1/CFT4_hel

The S-nitrosylation sites of O75717

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 1008 KNVLSETPAI C PPQNTENQRP   
2 156 PKDIFLASAS C DGSVRVWQIS   
3 598 HRGTGFDGDQ C LGVQLLELGK   
4 716 VAILSFKLPY C QIATEKGQME