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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Small subunit processome component 20 homolog

UniprotKB/SwissProt ID: O75691 (O75691)

Gene Name: UTP20

Organism: Homo sapiens (Human)

Function: Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. Involved in 18S pre-rRNA processing. Associates with U3 snoRNA

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus, nucleolus

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR016024 ARM-type_fold
IPR052575 SSU_processome_comp_20
IPR046523 UTP20_C
IPR011430 UTP20_N

The S-nitrosylation sites of O75691

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 1644 TAATEIIGAI C KHLSWSAYMY   
2 1730 RVDEEEKEYT C KSLSDNGQPG   
3 1757 SGGTSAKESE C ITKPVSFLPQ   
4 2058 APDPRLPPQS C LLLPPTPVRG   
5 2186 NFHLVVNCFK C VTILVKKVKS   
6 232 EGVGQLLFEM C KGVRNMFHSC   
7 2594 EQEALEDGVA C ADEKAESDGE   
8 618 LYYQRLALCG C KGPLSQEALM   
9 75 GKFYKEVIDK C QSFNQLVYHQ