Protein Name:
Cold shock domain-containing protein E1
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UniprotKB/SwissProt ID: O75534 (O75534)
Gene Name:
CSDE1
Organism: Homo sapiens (Human)
Function: RNA-binding protein involved in translationally coupled mRNA turnover (PubMed:11051545, PubMed:15314026). Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain (PubMed:11051545, PubMed:15314026). Required for efficient formation of stress granules (PubMed:29395067) (Microbial infection) Required for internal initiation of translation of human rhinovirus RNA
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm. Cytoplasm, Stress granule. Cytoplasm, P-body
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of O75534
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
129 |
APGQSPTGSV C YERNGEVFYL |
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| 2 |
186 |
IMLLKKKQAR C QGVVCAMKEA |
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| 3 |
191 |
KKQARCQGVV C AMKEAFGFIE |
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| 4 |
42 |
KLLTSYGFIQ C SERQARLFFH |
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| 5 |
464 |
AEDGIIAYDD C GVKLTIAFQA |
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| 6 |
506 |
KQRPGQQVAT C VRLLGRNSNS |
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| 7 |
53 |
SERQARLFFH C SQYNGNLQDL |
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| 8 |
680 |
ITPLRRATVE C VKDQFGFINY |
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| 9 |
730 |
SVILNQRTGK C SACNVWRVCE |
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