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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Enoyl-CoA delta isomerase 2

UniprotKB/SwissProt ID: O75521 (O75521)

Gene Name: ECI2

Organism: Homo sapiens (Human)

Function: Able to isomerize both 3-cis and 3-trans double bonds into the 2-trans form in a range of enoyl-CoA species. Has a preference for 3-trans substrates

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Mitochondrion. Peroxisome matrix

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR022408 Acyl-CoA-binding_prot_CS
IPR000582 Acyl-CoA-binding_protein
IPR035984 Acyl-CoA-binding_sf
IPR029045 ClpP/crotonase-like_dom_sf
IPR051053 ECH/Chromodomain_protein
IPR001753 Enoyl-CoA_hydra/iso
IPR014748 Enoyl-CoA_hydra_C
IPR014352 FERM/acyl-CoA-bd_prot_sf

The S-nitrosylation sites of O75521

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 312 FGKKLTAGEA C AQGLVTEVFP   
2 368 EKLHAVNAEE C NVLQGRWLSD   
3 380 VLQGRWLSDE C TNAVVNFLSR