Protein Name:
Mitochondrial-processing peptidase subunit beta
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UniprotKB/SwissProt ID: O75439 (O75439)
Gene Name:
PMPCB
Organism: Homo sapiens (Human)
Function: Catalytic subunit of the essential mitochondrial processing protease (MPP), which cleaves the mitochondrial sequence off newly imported precursors proteins (Probable) (PubMed:29576218). Preferentially, cleaves after an arginine at position P2 (By similarity). Required for PINK1 turnover by coupling PINK1 mitochondrial import and cleavage, which results in subsequent PINK1 proteolysis (PubMed:22354088)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Mitochondrion matrix
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of O75439
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
265 |
LAKFHFGDSL C THKGEIPALP |
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| 2 |
277 |
HKGEIPALPP C KFTGSEIRVR |
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| 3 |
389 |
HVVQKEWMRL C TSVTESEVAR |
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| 4 |
419 |
LLQLDGSTPI C EDIGRQMLCY |
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| 5 |
428 |
ICEDIGRQML C YNRRIPIPEL |
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| 6 |
485 |
PDFKQIRSNM C WLRD------ |
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| 7 |
62 |
VLNVPETRVT C LESGLRVASE |
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| 8 |
79 |
VASEDSGLST C TVGLWIDAGS |
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