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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Citrate synthase, mitochondrial

UniprotKB/SwissProt ID: O75390 (O75390)

Gene Name: CS

Organism: Homo sapiens (Human)

Function: Key enzyme of the Krebs tricarboxylic acid cycle which catalyzes the synthesis of citrate from acetyl coenzyme A and oxaloacetate

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Mitochondrion matrix

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR016142 Citrate_synth-like_lrg_a-sub
IPR016143 Citrate_synth-like_sm_a-sub
IPR002020 Citrate_synthase
IPR019810 Citrate_synthase_AS
IPR010109 Citrate_synthase_euk
IPR036969 Citrate_synthase_sf

The S-nitrosylation sites of O75390

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 101 IRFRGFSIPE C QKLLPKAKGG  CHHHHHHHHH H CCCCHHHHHH  3.47% 2212679
2 211 DSMDLIAKLP C VAAKIYRNLY  CHHHHHHHHH H CCCCHHHHHH  4.75% 22178444
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