UniprotKB/SwissProt ID: O75354 (O75354)
Gene Name:
ENTPD6
Organism: Homo sapiens (Human)
Function: Catalyzes the hydrolysis of nucleoside triphosphates and diphosphates in a calcium- or magnesium-dependent manner. Has a strong preference for nucleoside diphosphates, preferentially hydrolyzes GDP, IDP, and UDP, with slower hydrolysis of CDP, ITP, GTP, CTP, ADP, and UTP and virtually no hydrolysis of ATP (PubMed:10948193, PubMed:11041856, PubMed:14529283). The membrane bound form might support glycosylation reactions in the Golgi apparatus and, when released from cells, might catalyze the hydrolysis of extracellular nucleotides (PubMed:10948193, PubMed:11041856, PubMed:14529283)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Golgi apparatus membrane. Secreted. Cell membrane
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