Protein Name:
Liprin-alpha-2
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UniprotKB/SwissProt ID: O75334 (O75334)
Gene Name:
PPFIA2
Organism: Homo sapiens (Human)
Function: Alters PTPRF cellular localization and induces PTPRF clustering. May regulate the disassembly of focal adhesions. May localize receptor-like tyrosine phosphatases type 2A at specific sites on the plasma membrane, possibly regulating their interaction with the extracellular environment and their association with substrates. In neuronal cells, is a scaffolding protein in the dendritic spines which acts as immobile postsynaptic post able to recruit KIF1A-driven dense core vesicles to dendritic spines (PubMed:30021165)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm. Cell surface. Cell projection, dendritic spine
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of O75334
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
143 |
NTRLLLEHLE C LVSRHERSLR |
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