Protein Name:
Glycine receptor subunit alpha-3
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UniprotKB/SwissProt ID: O75311 (O75311)
Gene Name:
GLRA3
Organism: Homo sapiens (Human)
Function: Glycine receptors are ligand-gated chloride channels. Channel opening is triggered by extracellular glycine (PubMed:26416729, PubMed:9677400). Channel characteristics depend on the subunit composition; heteropentameric channels display faster channel closure (By similarity). Plays an important role in the down-regulation of neuronal excitability (By similarity). Contributes to the generation of inhibitory postsynaptic currents (By similarity). Contributes to increased pain perception in response to increased prostaglandin E2 levels (By similarity). Plays a role in cellular responses to ethanol (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Postsynaptic cell membrane. Perikaryon. Cell projection, dendrite. Synapse. Cell membrane
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Graphical Visualization of S-nitrosylation Sites:
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