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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Gamma-glutamylcyclotransferase

UniprotKB/SwissProt ID: O75223 (O75223)

Gene Name: GGCT

Organism: Homo sapiens (Human)

Function: Catalyzes the formation of 5-oxoproline from gamma-glutamyl dipeptides and may play a significant role in glutathione homeostasis (PubMed:18515354). Induces release of cytochrome c from mitochondria with resultant induction of apoptosis (PubMed:16765912)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization:

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR017939 G-Glutamylcylcotransferase
IPR013024 GGCT-like
IPR036568 GGCT-like_sf

The S-nitrosylation sites of O75223

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 42 HLRNPSAAFF C VARLQDFKLD