Protein Name:
DnaJ homolog subfamily C member 13
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UniprotKB/SwissProt ID: O75165 (O75165)
Gene Name:
DNAJC13
Organism: Homo sapiens (Human)
Function: Involved in membrane trafficking through early endosomes, such as the early endosome to recycling endosome transport implicated in the recycling of transferrin and the early endosome to late endosome transport implicated in degradation of EGF and EGFR (PubMed:18256511, PubMed:18307993). Involved in the regulation of endosomal membrane tubulation and regulates the dynamics of SNX1 on the endosomal membrane; via association with WASHC2 may link the WASH complex to the retromer SNX-BAR subcomplex (PubMed:24643499)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Early endosome. Early endosome membrane. Endosome membrane
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of O75165
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
1262 |
FCNIYYLKQL C DTLRFPDWPI |
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| 2 |
1432 |
ATELAFHTVN C SALNAEELRR |
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| 3 |
1480 |
SVQVCGYISK C YSVAAQFEEC |
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| 4 |
149 |
QINPATNRVL C SYDYRNIEGF |
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| 5 |
2110 |
KKRADTVGLA C EAINRMFQKE |
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| 6 |
820 |
NHHEFEVKYE C LAEEIKIGDY |
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