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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Huntingtin-interacting protein 1-related protein

UniprotKB/SwissProt ID: O75146 (O75146)

Gene Name: HIP1R

Organism: Homo sapiens (Human)

Function: Component of clathrin-coated pits and vesicles, that may link the endocytic machinery to the actin cytoskeleton. Binds 3-phosphoinositides (via ENTH domain). May act through the ENTH domain to promote cell survival by stabilizing receptor tyrosine kinases following ligand-induced endocytosis

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm, perinuclear region. Endomembrane system. Cytoplasmic vesicle, clathrin-coated vesicle membrane

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR011417 ANTH_dom
IPR013809 ENTH
IPR008942 ENTH_VHS
IPR032422 HIP1_clath-bd
IPR035964 I/LWEQ_dom_sf
IPR002558 ILWEQ_dom
IPR030224 Sla2_fam

The S-nitrosylation sites of O75146

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 211 IAVSQMSSGQ C RLAPLIQVIQ   
2 650 SKLDDPLHLR C TSSPDYLVSR