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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Kinesin-like protein KIF21B

UniprotKB/SwissProt ID: O75037 (O75037)

Gene Name: KIF21B

Organism: Homo sapiens (Human)

Function: Plus-end directed microtubule-dependent motor protein which displays processive activity. Is involved in regulation of microtubule dynamics, synapse function and neuronal morphology, including dendritic tree branching and spine formation. Plays a role in lerning and memory. Involved in delivery of gamma-aminobutyric acid (GABA(A)) receptor to cell surface

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm, cytoskeleton. Cell projection, dendrite. Cell projection, growth cone. Cell projection, axon. Cytoplasmic vesicle

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR056533 KIF21A/B_hel_1
IPR056532 KIF21A/B_hel_2
IPR027640 Kinesin-like_fam
IPR019821 Kinesin_motor_CS
IPR001752 Kinesin_motor_dom
IPR036961 Kinesin_motor_dom_sf
IPR027417 P-loop_NTPase
IPR015943 WD40/YVTN_repeat-like_dom_sf
IPR019775 WD40_repeat_CS
IPR036322 WD40_repeat_dom_sf
IPR001680 WD40_rpt

The S-nitrosylation sites of O75037

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 1382 KVWDIRDSAK C IRTLTSSGQV   
2 1398 SSGQVISGDA C AATSTRAITS   
3 1488 HYVKMFELGE C VTGTIGPTHN   
4 1621 LWNYVPGLTP C LPRRVLAIKG   
5 234 RSHAIFTIHL C QMRMCTQPDL    37478858
6 641 NFQADLADLT C EIEIKQKLID   
7 67 DTWQEQIYST C VSKLIEGCFE   
8 999 IDYINDGITD C QATIVQLEET