Protein Name:
Sphingomyelin phosphodiesterase 2
|
UniprotKB/SwissProt ID: O70572 (O70572)
Gene Name:
Smpd2
Organism: Mus musculus (Mouse)
Function: Catalyzes, at least in vitro, the hydrolysis of sphingomyelin to form ceramide and phosphocholine (PubMed:9520418). Also hydrolyzes 1-O-alkyl-2-lyso-sn-glycero-3-phosphocholine (lyso-platelet-activating factor) in vivo (By similarity). Also acts on 1-acyl-2-lyso-sn-glycero-3-phosphocholine (lyso-PC) and sphingosylphosphocholine (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cell membrane
|
|
|
Graphical Visualization of S-nitrosylation Sites:
|
|
The S-nitrosylation sites of O70572
|
| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
176 |
TSKNADVVLL C GDLNMHPKDL |
CCCCEEEEEE E EECCCCCCHH |
3.31% |
21278135
|
| 2 |
411 |
DRGSEPHLAY C LQQEGDRA-- |
CCCCEEEEEE E EECCCCCCHH |
1.99% |
21278135
|
|
