Protein Name:
5-hydroxytryptamine receptor 4
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UniprotKB/SwissProt ID: O70528 (O70528)
Gene Name:
HTR4
Organism: Cavia porcellus (Guinea pig)
Function: G-protein coupled receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone and a mitogen. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors. HTR4 is coupled to G(s) G alpha proteins and mediates activation of adenylate cyclase activity
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cell membrane. Endosome membrane
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Graphical Visualization of S-nitrosylation Sites:
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