UniprotKB/SwissProt ID: O70373 (O70373)
Gene Name:
Xirp1
Organism: Mus musculus (Mouse)
Function: Protects actin filaments from depolymerization (By similarity). Required for correct cardiac intercalated disk ultrastructure via maintenance of cell-cell adhesion stability, and as a result maintains cardiac organ morphology, conductance and heart beat rhythm (PubMed:17766470). Required for development of normal skeletal muscle morphology and muscle fiber type composition (PubMed:25582411). Plays a role in regulating muscle satellite cell activation and survival, as a result promotes muscle fiber recovery from injury and fatigue (PubMed:25582411)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cell junction, adherens junction. Cell junction, desmosome. Cell junction
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